logo libreria universo

Libreria Universo - (Adiacenze Policlinico Umberto I) - Orario di apertura: dal Lunedi al Venerdi dalle 07:30 alle 19:00, Sabato dalle 09:00 alle 13:00.
Piazza Girolamo Fabrizio, 6 - 00161 - Roma - email: info@libreriauniverso.it - Tel. 06-490931 - Fax 06-4451407

Libreria Universo Due - (Adiacenze Policlinico Gemelli) - Orario di apertura: dal Lunedi al Venerdi dalle 09:30 alle 13:30 e dalle 14:00 alle 19:00.
Via Agenore Zeri, 11 - 00168 - Roma - email: info@libreriauniverso.it - Tel. 06-64561499 - Fax 06-64831480

copertina di Drug Resistance in the Treatment of Cancer

Drug Resistance in the Treatment of Cancer

di Pinedo - Giaccone - Sikora  • 2007  • dettagli prodotto


Reviews the mechanisms and clinical implications of drug resistance in cancer, considered to be the most significant obstacle to the cure of cancer today. Topics covered include multiple drug resistance and its reversal, topoisomerase drugs, apoptosis, dose intensity and escalation, gene therapy and haematopoietic support.Table of Contents List of contributorsSeries editor's prefaceAbbreviations1. Resistance mechanisms to antimetabolites Erdem Göker, Richard Gorlick and Joseph R. Bertino2. Resistance to antitumor alkylating agents and cisplatin Beverly A. Teicher and Emil Frei III3. The MDR genes Lyn Mickley and Antonio Tito Fojo4. Topoisomerase genes and resistance to topoisomerase inhibitors Giuseppe Giaccone5. Genes that modulate apoptosis: major determinants of drug resistance John A. Hickman6. Clinical implications of drug resistance Henk M. W. Verheul and Herbert M. Pinedo7. The reversal of multidrug resistance William S. Dalton8. Effect of dose and schedule on chemotherapeutic drug resistance David Fennelly, George Raptis, John P. A. Crown and Larry Norton9. Circumvention of drug resistance by high-dose chemotherapy in solid tumors Elisabeth G. E. de Vries, Wil Dolsma, Geke A. P. Hospers and Nanno H. Mulder10. Enhancing drug effectiveness by gene transfer Karol SikoraIndex.


ISBN: 9780521030748

Titolo: Drug Resistance in the Treatment of Cancer


Editore: Cambridge University Press

Volume: Unico

Edizione: 2007

Lingua: Inglese

Finitura: Copertina flessibile

Pagine: 340

Peso: 0.5 kg