logo libreria universo

Libreria Universo - (Adiacenze Policlinico Umberto I) - Orario di apertura: dal Lunedi al Venerdi dalle 07:30 alle 19:00, Sabato dalle 09:00 alle 13:00.
Piazza Girolamo Fabrizio, 6 - 00161 - Roma - email: info@libreriauniverso.it - Tel. 06-490931 - Fax 06-4451407

Libreria Universo Due - (Adiacenze Policlinico Gemelli) - Orario di apertura: dal Lunedi al Venerdi dalle 09:30 alle 13:30 e dalle 14:00 alle 19:00.
Via Agenore Zeri, 11 - 00168 - Roma - email: info@libreriauniverso.it - Tel. 06-64561499 - Fax 06-64831480

copertina di The Aetiology of Deep Venous Thrombosis - A Critical  Historical and Epistemological ...

The Aetiology of Deep Venous Thrombosis - A Critical Historical and Epistemological Survey

di Malone - Agutter  • 2008  • dettagli prodotto

DESCRIZIONE

What we now call ‘deep venous thrombosis’ (DVT) has been elucidated by a diversity of investigative approaches during the past four centuries. The authors of this book survey the history of the field and ask: why has one of these perspectives – the haematological/biochemical – come to dominate research into the causation of DVT during the past 50 years and to exclude alternatives? In answering this question, the authors show that the current consensus model is conceptually flawed. Building on the work of William Harvey, John Hunter, Rudolf Virchow, Ludwig Aschoff and a number of pathologists in the mid-20th century, they offer a revised account of the aetiology of this condition. In the process they retrace and review the 160-year-old philosophical and methodological schism in biomedical research and, using DVT as an example, propose how this schism might be bridged to the benefit of both research and clinical practice.Table of contents Preface.- Acknowledgments.- Synopsis.- Introduction to the study of deep venous thrombosis.-The coagulation cascade and the consensus model of DVT.- Hypercoagulability.- Historical roots.- Coagulation and its disorders: a history of haematological research.- Virchow and the pathophysiological tradition in the 19th century.- The pathophysiological tradition after Virchow.- Interrupted circulation: the ‘stasis’ hypothesis and the significance of venous valves.- Underperfusion of valve pockets and the initiation of VVP.- The role of endothelial hypoxia in DVT.-The valve cusp hypoxia hypothesis.- Molecular changes in the hypoxic endothelium.- Cadaver blood or agonal thrombi?- Appendix: science, medicine and philosophy.

DETTAGLI PRODOTTO  torna su

ISBN: 140206649X

Titolo: The Aetiology of Deep Venous Thrombosis - A Critical Historical and Epistemological Survey

Autori:

Editore: Springer Verlag

Volume: Unico

Edizione: 2008

Lingua: Inglese

Finitura: Copertina rigida

Pagine: 322