Advances in DNA Repair in Cancer Therapy
di Panasci - Aloyz - Alaoui Jamali • 2013 • dettagli prodotto
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DESCRIZIONE
This book deals with the emerging role of various DNA repair proteins and the regulatory elements which are implicated in cancer therapy such as DNA cross-linking agents, radiotherapy and bleomycin. The DNA repair genes discussed include those involved in BRCA/Rad51-related homologous recombinational repair, DNA-PK related nonhomologous endjoining and the nucleotide excision repair gene, ERCC1. Moreover, the role of regulatory genes such as PARP, ATR, telomerase, growth factor receptors and downstream kinase signalling is examined.
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ISBN: 9781461447405
Titolo: Advances in DNA Repair in Cancer Therapy
Autori: Panasci - Aloyz - Alaoui Jamali
Editore: Springer Verlag
Volume: Unico
Edizione: 2013
Collana: Cancer Drug Discovery and Development
Lingua: Inglese
Finitura: Copertina rigida
Pagine: 312
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