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Bipolar Depression - Molecular Neurobiology - Clinical Diagnosis and Pharmacotherapy

di Carlos - Manji  • 2008  • dettagli prodotto

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DESCRIZIONE

This book is a thorough overview of bipolar depression aimed primarily at researchers, clinicians, and postgraduate students. Although our knowledge of mood disorders in general is expanding steadily, comparatively little is known about bipolar depression in particular. This book brings together clinicians and researchers to offer the most up-to-date information about the diagnosis, treatment, and research surrounding bipolar depression. The book begins by providing valuable diagnostic information, allowing clinicians to distinguish between the various mood disorders. Early chapters review the course and outcome and genetics of this highly heritable condition. The book also offers a thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work. Several chapters delineate the treatment of bipolar depression in special populations such as children and pregnant women, and another chapter addresses the particular issues of suicide, focusing on the need for assessment during both acute and maintenance treatment with interventions appropriate to a patient's symptoms and history. Finally, the book covers acute and long-term treatment strategies for bipolar depression, including both traditional and novel therapeutics for the disorder, as well as non-pharmacological treatments. Despite the devastating impact of bipolar depression on the lives of millions worldwide, there has been a dearth of knowledge concerning its underlying etiology and pathophysiology. This dearth, in turn, has undoubtedly contributed to the lack of development of improved therapeutic strategies for bipolar depression. This book has assembled a widelyrespected group of preclinical and clinical researchers who bring their expertise to bear upon this illness. It offers both researchers and clinicians key insights into this devastating disorder.Table of contents The history of bipolar disorders.- The clinical diagnosis of bipolar depression.- Course and outcome of bipolar disorder – focusing on depressive aspects.- Suicide and bipolar disorder.- The genetic basis of bipolar disorder.- Understanding the neurobiology of bipolar depression.- Non-pharmacological treatments and chronobiological aspects of bipolar disorder: implications for novel therapeutics.- Neuroimaging studies of bipolar depression: therapeutic implications.- Pharmacological treatment of acute bipolar depression.- Pharmacological treatment of the maintenance phase of bipolar depression: focus on relapse prevention studies and the impact of design on generalizability.- Non-pharmacological somatic treatments for bipolar depression.- Potential novel treatments for bipolar depression.- Late-onset bipolar disorder.- Treatment of childhood-onset bipolar disorder.- Treatment of bipolar disorder during and after pregnancy.- Conclusion

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ISBN: 3764385669

Titolo: Bipolar Depression - Molecular Neurobiology - Clinical Diagnosis and Pharmacotherapy

Autori:

Editore: Springer Verlag

Volume: Unico

Edizione: 2008

Lingua: Inglese

Finitura: Copertina rigida

Pagine: 250

RECENSIONI

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