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copertina di Bortezomib in the Treatment of Multiple Myeloma

Bortezomib in the Treatment of Multiple Myeloma

di Ghobrial - Richardson - Anderson  • 2010  • dettagli prodotto

spedizione gratuita
normalmente disponibile
per la spedizione in 10-15 giorni lavorativi


Multiple Myeloma (MM) is the second most common type of blood cancer, resulting from an overproduction of cancerous infection-fighting white blood cells, known as plasma cells. Plasma cells are a crucial part of the immune system responsible for the production of antibodies. Bortezomib is a promising anticancer drug targeting the proteasome. This proteasome inhibitor induces cell stress and apoptosis in the cancer cells. While multiple mechanisms are likely to be involved, proteasome inhibition may prevent the degradation of pro-apoptotic factors, permitting activation of programmed cell death in neoplastic cells dependent upon the suppression of proapoptotic pathways. This monograph on bortezomib is a valuable source of information for researchers and clinicians from the fields of oncology and pharmacology, working either in academia or the pharmaceutical industry.


ISBN: 9783764389475

Titolo: Bortezomib in the Treatment of Multiple Myeloma


Editore: Springer Verlag

Volume: Unico

Edizione: 2010

Lingua: Inglese

Finitura: Copertina rigida

Pagine: 179