logo libreria universo

Libreria Universo - (Adiacenze Policlinico Umberto I) - Orario di apertura: dal Lunedi al Venerdi dalle 07:30 alle 19:00, Sabato dalle 09:00 alle 13:00.
Piazza Girolamo Fabrizio, 6 - 00161 - Roma - email: info@libreriauniverso.it - Tel. 06-490931 - Fax 06-4451407

Libreria Universo Due - (Adiacenze Policlinico Gemelli) - Orario di apertura: dal Lunedi al Venerdi dalle 09:30 alle 13:30 e dalle 14:00 alle 19:00.
Via Agenore Zeri, 11 - 00168 - Roma - email: info@libreriauniverso.it - Tel. 06-64561499 - Fax 06-64831480

Genome Stability and Human Diseases

di Nasheuer  • 2010  • dettagli prodotto

spedizione gratuita
normalmente disponibile
per la spedizione in 20-25 giorni lavorativi
Paga gli acquisti tra 30€ e 2.000€ in 3 rate
senza interessi. Scopri di più

DESCRIZIONE

Since the establishment of the DNA structure researchers have been highly interested in the molecular basis of the inheritance of genes and of genetic disorders. Scientific investigations of the last two decades have shown that, in addition to oncogenic viruses and signalling pathways alterations, genomic instability is important in the development of cancer. This view is supported by the findings that aneuploidy, which results from chromosome instability, is one of the hallmarks of cancer cells. Chromosomal instability also underpins our fundamental principles of understanding tumourigenesis: It thought that cancer arises from the sequential acquisition of genetic alterations in specific genes. In this hypothesis, these rare genetic events represent rate-limiting ‘bottlenecks’ in the clonal evolution of a cancer, and pre-cancerous cells can evolve into neoplastic cells through the acquisition of somatic mutations

DETTAGLI PRODOTTO  torna su

ISBN: 9789048134700

Titolo: Genome Stability and Human Diseases

Autori:

Editore: Springer Verlag

Volume: Unico

Edizione: 2010

Lingua: Inglese

Finitura: Copertina rigida

Pagine: 390

RECENSIONI

NESSUNA RECENSIONE PER QUESTO PRODOTTO