Cyclopenta ( a ) phenanthrenes

di Coombs • 2008 • dettagli prodotto

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DESCRIZIONE

This volume looks in detail at the chemistry and carcinogenicity of the cyclopenta[a]phenanthrenes and covers all aspects of this class of compounds including their chemical syntheses and chemistry, occurrence, physical and spectral properties, metabolism, carcinogenicity and mutagenicity.Table of Contents Author's preface1. Introduction2. Chemical synthesis of cyclopenta[a]phenanthrenes: hydrocarbons3. Chemical synthesis of cyclopent[a]phenanthenes: ring-D ketones4. General chemistry of cyclopenta[a]phenanthrenes5. Physical and spectral properties of cyclopenta[a]phenanthrenes6. Carcinogenicity and mutagenicity of cyclopenta[a]phenanthrenes7. Metabolic activation of cyclopenta[a]phenanthrenes and their interaction with DNA8. X-ray crystallography of some cyclopenta[a]phenanthrenes: an apparent correlation between molecular strain and carcinogenicity9. ConclusionGeneral Index.