The Epidemiology of Schizophrenia

di Murray - Jones - Susser - Van Os - Cannon • 2002 • dettagli prodotto

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DESCRIZIONE

A comprehensive, epidemiological overview of schizophrenia, drawing together the findings from social, genetic, developmental and classical epidemiology. Controversial issues on its nature and cause are explored in depth, and separate chapters are devoted to suicide, violence and substance abuse, new prospects for treatment, and prevention.Table of Contents •. List of contributors. . . Preface. . . Foreword. . I. The social epidemiology of schizophrenia. . 1. Investigating socioenvironmental influences in schizophrenia: conceptual and design issues. 5. 2. Geographical variation in incidence, course and outcome of schizophrenia: a comparison of developing and developed countries. 18. 3. Temporal variation in the incidence, course and outcome of schizophrenia. 34. 4. Urbanization, migration and risk of schizophrenia. 49. II. The developmental epidemiology of schizophrenia. . 5. Prenatal and perinatal risk factors for schizophrenia. 74. 6. Childhood development and later schizophrenia: evidence from genetic high-risk and birth cohort studies. 100. 7. Prodrome, onset and early course of schizophrenia. 124. 8. The value of first-episode studies in schizophrenia. 148. 9. Schizophrenia at the extremes of life. 167. III. The genetic epidemiology of schizophrenia. . 10. The 'classical' genetic epidemiology of schizophrenia. 194. 11. Molecular genetics and epidemiology in schizophrenia: a necessary partnership. 220. 12. Gene-environment correlation and interaction in schizophrenia. 235. 13. Investigating gene-environment interaction in schizophrenia using neuroimaging. 254. IV. Special issues in the epidemiology of schizophrenia. . 14. Mortality and physical illness in schizophrenia. 275. 15. The clinical epidemiology of suicide in schizophrenia. 288. 16. What is the relationship between substance abuse and schizophrenia?. 317. 17. Criminal and violent behaviour in schizophrenia. 343. V. Future directions and emerging issues. . 18. Diagnosis and classification of schizophrenia: categories versus dimensions, distributions versus disease. 364. 19. The implications of epidemiology for service planning in schizophrenia. 411. 20. Prevention of schizophrenia - not an impossible dream. 427. . Glossary of epidemiological terms. 441. . Index. 447.