Brings together oncologists, neurosurgeons, physicians, research scientists, and pathologists in the field of autophagy to discuss cutting-edge developments in this rapidly-advancing fieldBuilds upon recent advances in genome-scale approaches and computational tools to discuss the advances in regulation of autophagy at the systems level. Organized for readers into easy-to-access sections: molecular mechanisms; role of autophagy in disease; role of autophagy in cancer; and autophagy and apoptosis. Explores exciting new developments, including the measurement of autophagic flux; the molecular role of the Atg12-Atg5-Atg16 complex; and the molecular bases of autophagosome formation in yeast.
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Titolo: Autophagy : Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging - Role in Specific Diseases
Editore: Elsevier - Academic Press
Finitura: Copertina rigida
Misure: 19x23 cm
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