They fall into two separate categories, one a disaster, the other a triumph. The disaster is, of course, the HIV/AIDS epidemic which has resulted in an epidemic of opportunistic infection around the world. However, since the summer of 1981, when AIDS was first recognized, remarkable progress has been made- the etiology and pathogenesis of AIDS have been established; diagnosis and prognosis (viral load and CD4-positive lymphocyte counts) have been defined; and HAART (Highly Active Anti-Retroviral Therapy) therapy has become the standard of care. Despite drug toxicities and interactiions, despite high costs, and despite problems with drug resistance, HAART therapy has made a major difference in the lives of those infected with HIV. At the same time, AIDS in its many forms is no longer a conditiion relegated to ivory towers and academicians. It is now the province of all practitioners, and the requirements for expertise are the province of primary care physicians as well as academicians.
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Titolo: Clinical Approach to Infection in the Compromised Host
Autori: Rubin - Young
Editore: Springer Verlag